How Long Does It Take For Metformin To Work?

PCOS - Polycystic Ovary Syndrome - Picture of healthy ovary vs polycystic ovary

Polycystic ovary syndrome (PCOS) affects your ability to get pregnant because it can cause irregular periods and a lack of regular ovulation. It takes time for Metformin to work. Regular menstrual cycles usually return within about six months in women with PCOS taking Metformin.  

Why is Metformin used?

Metformin, also known as Glucophage, is a medication used to regulate the levels of glucose (sugar) in the blood. Metformin accomplishes its task through three methods:

  1. It causes the liver to produce less glucose.
  2. Metformin helps your stomach to absorb less glucose from the food that you eat.
  3. Metformin improves the efficiency of the insulin that the body produces, reducing the amount of glucose in your blood.

Doctors often prescribe Metformin for people with Type II diabetes and sometimes prescribe it if you have been diagnosed with PCOS. It’s effective in helping to reverse insulin resistance in women with polycystic ovarian syndrome (PCOS). Metformin can also help regulate your menstrual cycle and ovulation. Metformin is most effective when used in combination with diet and exercise.

If you have not had an adequate response to other types of treatment, Metformin may be your best option. Metformin side effects are usually mild, and many people do not experience any at all.

How Metformin Is Used for Polycystic Ovaries

Polycystic ovary syndrome (PCOS) is a common cause of anovulation and infertility in women. These women don’t ovulate (release eggs) regularly and therefore have irregular menstrual periods.

The ovaries are studded with thousands of small cysts, which may appear as solid lumps in an ultrasound scan. This condition is called a ‘polycystic’ (many cysts) appearance of the ovaries.

Some women ovulate spontaneously without using any additional medications. However, if Glucophage (Metformin) alone doesn’t help them get pregnant, they often use:

Clomid and Metformin taken together will cause ovulation in about 85% of cases in women who are not taking birth control pills or are using one that does not suppress ovulation.

Health Benefits of Taking Metformin for Women with PCOS

People who have Polycystic Ovary Syndrome (PCOS) should also consider using Metformin to help control their blood sugar levels and many other health problems. It helps control sugar levels and reduce cholesterol and blood fats.

PCOS can cause many problems with ovulation and irregular menstrual cycles, which makes it difficult to conceive. Metformin can increase your chances of getting pregnant and regulate menstruation, allowing your body to get ready for a pregnancy.

Polycystic ovary syndrome (PCOS) is a complex disorder that increases your chances of having a miscarriage. Metformin lowers the risk of miscarriage in women with PCOS. 

This medication may also help women with polycystic ovary syndrome (PCOS) who are overweight by delaying or preventing full-blown diabetes from developing. It may also help control weight.

Common Questions Asked About Metformin


What Are the Side Effects of Metformin?

Metformin has some common side effects: nausea, diarrhea, heartburn, indigestion, stomach aches, fatigue, cramps, and headaches. Some people have experienced other side effects, too. Allergic reactions like skin rashes, hives, or breathing problems can occur.

Is Metformin Safe for Pregnant Women?

Metformin is safe for pregnant women. Your doctor should monitor your blood sugar levels closely during your pregnancy.

Does Metformin interact with other medications?

The most common drug interactions are those involving birth control pills. Your doctor will be able to help you determine whether your birth control pills need to be adjusted or changed to ensure that you do not have any problems with Metformin. In general, if you take a combination pill that includes both estrogen and progestin, you should avoid taking Metformin simultaneously.

If you take birth control pills containing only progesterone, there is no need to avoid taking Metformin. 

Can I take Metformin with food?

You can take Metformin with or without food. Some people find it easier to take the medication when they do not eat before taking the medication. You may also feel less nauseated if you do not eat for a few hours before taking the Metformin.